About the Position:

The Weems Lab at UT Austin is seeking a curious and driven microscopy technician to assist in the building and maintenance of two lightsheet microscopy systems. Experience building such custom imaging systems is desirable but not required, so long as the applicant is capable and committed to learning and mastering this skillset. Significant collaboration will take place between our lab and the labs in which these systems were first developed, including overnight travel for offsite training at the UT Southwestern Medical Center in Dallas.

Responsibilities:

• Assist in the building and maintenance of custom lightsheet microscopes
• Collect cell biological lightsheet imaging data
• Train and assist biologists in the operation of these systems

Qualifications:

Required: Bachelor’s degree or higher in a scientific, engineering, or technical field relating to microscopy or optical engineering, as well as laboratory experience with fluorescence microscopy. Relevant education and experience may be substituted as appropriate. Preferred: Experience constructing and maintaining custom open beam microscopy systems; experience with gaussian light sheet microscopy; experience performing microscopal cell biology experiments.

Compensation:

$50,000 + depending on qualifications, w/ benefits

We are currently seeking an enthusiastic and proactive Postdoctoral Research Associate to join our dynamic laboratory at the Rosalind Franklin Institute. If you are a creative scientist that want to explore novel venues on quantitative imaging biology, join us. Our lab is interested in Molecular Organisation of Cell Interfaces in the epithelial tissue and in pathology of intestinal diseases. We use super-resolution STED microscopy in combination with gut organoids, biophysics & chemical biology to uncover how epithelial cells organise in space and time under different physico-chemical environments to drive self-organisation processes that shape mesoscale structures enabling tissue function. 

A full time, permanent position in the Microscope Facility in the College of Medicine and Health at the University of Birmingham is available.

Please share with those that might be interested and in your networks.

Closing date 12th January.

Role Summary This position requires rich experience in pharmacokinetics and pharmacodynamics assessment. The platform technical lead needs to be familiar with most processes of preclinical PK/PD analysis, and have experience in PK/PD project design, experimental team formation, and laboratory management. The candidate will help Creative Biolabs expand the PK/PD assessment contract business. Excellent communication, collaboration, strategic thinking, decision making, negotiation, and influencing skills, and the ability to solve complex problems and manage complex projects are required.

Position Responsibilities Play a key role in developing new strategies, techniques, and instruments for new ventures and critical issues in the preclinical PK/PD area. Lead cross-functional Technical Development Teams. Establish a novel preclinical PK/PD analysis platform. Design and execute novel technical development strategies that enable successful licensure of novel modalities (e.g., novel/advanced safety assessment technology), and build new capabilities for the company (e.g., establishment of new technologies, process development and/or manufacturing facilities). Contribute to long-range planning and technical policies of the department.

Education and Experience Advanced degree in pharmacokinetics/pharmacodynamics or a related discipline in pharmaceutical sciences. Recognized by research peers as an expert in a selected technical field. 5-7 years of experience in preclinical drug discovery and development, including small molecule and protein/monoclonal antibody therapeutics.

Technical Skill Requirements Highly skilled in conducting research, data interpretation, and writing reports. Ability to design and execute preclinical PK/PD analysis projects. Excellent verbal and written communication skills with success in influencing others in cross-functional areas. Proven ability to work proactively and think strategically. For people with special skills, we can also cooperate in the form of consultant/part-time job/partnership.

Division PK/PD

Microscopy and CT-scanning image analysis expert

Operator of the CT-scanner at the Multi-Scale Imaging Facility

About Us

We are looking for a talented Research Microscopy Specialist with a passion and aptitude for maintaining, developing and managing light microscopes to join the Centre for Developmental Neurobiology, King’s College London.   The Centre currently houses a number of different microscopes, ranging from laser scanning confocal and 2-photon microscopes, to wide-field imaging microscopes that incorporate super-resolution microscopy and light sheet imaging. The candidate will need to be familiar with these different imaging techniques. In line with the diversity of imaging approaches in the Centre, the candidate will be expected to actively interact with researchers to not only maximise imaging conditions of existing microscopes, but also develop and help implement new imaging modalities.   The Centre is based on the Guy’s Campus of King’s College London providing an intellectually stimulating environment, state-of-the-art facilities, and excellent career development opportunities.  

About the Role

You will take up a central role in the upkeep and maintenance of microscopes used by researchers at Centre for Developmental Neurobiology. If successful, you will also provide help with training researchers and carrying out inductions to ensure proper usage of the microscope.   This is a full-time post (35 Hours per week), and you will be offered an indefinite contract.  

About You

To be successful in this role, we are looking for candidates to have the following skills and experience:  Essential criteria  

1. Degree in life sciences or physical sciences or equivalent experience.
2. Experience with different imaging/microscopy techniques
3. Expertise in optimising and/or fine-tuning microscopes.
4. Knowledge of biological sciences
5. Knowledge of fluorescence imaging techniques in biological science across multiple imaging modalities
6. Ability to work in close collaboration within a team
7. A broad understanding of effective approaches to train microscope users in imaging methodologies and techniques. Desirable criteria
8. Knowledge of neuroscience
9. Expertise with image analysis and processing across multiple imaging modalities
10. Experience with optogenetic approaches
11. Expertise with developing/building microscopes

Downloading a copy of our Job Description Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, provided at the bottom of the next page after you click “Apply Now”. This document will provide information of what criteria will be assessed at each stage of the recruitment process.

Further Information

We pride ourselves on being inclusive and welcoming. We embrace diversity and want everyone to feel that they belong and are connected to others in our community. We are committed to working with our staff and unions on these and other issues, to continue to support our people and to develop a diverse and inclusive culture at King's.   We ask all candidates to submit a copy of their CV, and a supporting statement, detailing how they meet the essential criteria listed in the advert. If we receive a strong field of candidates, we may use the desirable criteria to choose our final shortlist, so please include your evidence against these where possible.   To find out how our managers will review your application, please take a look at our ‘How we Recruit’ pages.   We are able to offer sponsorship for candidates who do not currently possess the right to work in the UK.

About the position: The Image Analysis Associate will join the Cimini lab to aid in processing and extracting quantitative information from microscopy images. Primary duties will include tuning and applying image analysis pipelines and documenting project methods and metrics. The Associate will use project management skills to track multiple datasets across multiple projects. Additional duties will be tailored based on project needs and Associate interests but could include broader training in image analysis, coding, and/or data science components of existing projects.

The Image Analysis Associate will gain expertise in using CellProfiler, an image analysis software that our lab develops and maintains, and cloud-based workflows, especially Distributed-CellProfiler run in Amazon Web Services.    Requirements

• B.A. in biology or similar field
• Substantial experience with light microscopy and some experience using image processing software on biological assays 
• A personality that is helpful, professional, highly organized, and goal-oriented, efficiently juggling projects and competing demands while tracking time spent on each task and monitoring deliverables
• Able to clearly communicate with biology collaborators about project aims and results, and with software engineers on the team about image processing and software needs Useful but not required: CellProfiler expertise, Python programming experience, and experience with Linux environments, cloud computing clusters, and CLIs.

About us: Our lab’s mission is to uncover biological knowledge by developing advanced methods to quantify and mine the rich information present in images. We love working as a team towards scientific goals: discovering the inner workings of biological systems and influencing patient treatment. We love making open-source software that impacts the world. We are conscientious and enjoy a professional, no-fuss environment, and are passionate about what we do while frowning on workaholism. In correspondence to us, please describe your overall career interests, why this work would suit you, and what you would aim to learn. Apply online at Broad Careers posting #40753. Note that this is a Broad-wide posting, so please do mention the Imaging Platform/Cimini lab specifically to ensure your application is routed correctly to us.

Impact the discovery of new disease therapies at the Cimini laboratory (Imaging Platform) Join our vibrant, world-class, non-profit biomedical research center, the Broad Institute!

Our lab’s mission is to uncover biological knowledge by developing methods to mine the rich information present in images. We are best known for CellProfiler, used by scientists to quantify biological images and have recently launched Piximi, an images-to-discovery tool allowing users to train deep learning models in the browser. CellProfiler helped discover potential therapeutics for infectious diseases and cancers. We love working as a team towards scientific goals: discovering the inner workings of biological systems and influencing patient treatment. We are conscientious and enjoy a professional, no-fuss environment, and are passionate about what we do while frowning on workaholism.

In your cover letter, please describe your overall career interests, why this work would suit you, and what you would aim to learn.

Our laboratory co-leads the Center for Open Bioimage Analysis, funded by the National Institutes of Health (NIH). Join our cross-functional, agile team spanning biology, computer science, and software engineering and help write and maintain user-friendly and open-source applications to process and analyze biological images.

• You are experienced with contemporary programming, testing, and debugging techniques.
• You have working experience with modern Python development paradigms, libraries, and tools.
• You have working experience in scientific programming.
• You have an interest in optimizing and scaling existing systems.
• You have outstanding personal initiative and communication skills; you will extensively collaborate with other software engineers as well as biologists.

Requirements:

• BS/BA in Computer Science, Bioinformatics, Mathematics, Physics, or a related degree
• 0-2 years of software engineering experience, preferably in a scientific setting

We are looking for a Research Software Engineer to kick start the next phase of our development. If you are passionate about open science and want to contribute to creating shareable, accessible, and open resources, this is the role for you. Your first mission will be to drive OME-Zarr, a Next-Generation File Format (NGFF) to support scalable, cloud-based, multi-modal bioimaging data storage and management. As our network of collaborators grows, your role will evolve with new and exciting challenges.

🌟We are looking for a new member of our image analysis team at the Imaging Core Facility of the Biozentrum in Basel 🌟 Are you passionate about science and technology? Are you interested in bioimaging? Please check the job ad by following the link

JobOpportunity #ImageAnalysis #DeepLearning

Exciting Advanced Imaging Specialist job at our COMPARE Advanced Microscopy Facility in Birmingham! Great opportunity to lead our state-of-the-art facility that houses 9 commercial and several custom systems, open to the wide biomedical research community! Applications close on the 11th November. Get in touch if you have any questions and please share widely!

The Microscopy Specialist Technician will be responsible for providing a full support to customers on multiple technologies. This will include giving specialist advice about the offering and match that to the user requirement. The specialist will use advanced skills to support maintenance and in-depth training of the equipment offering at the facility for users.  They will need to develop constructive working relationships with a wide range of stakeholders (both internal and external) and use project management skills to coordinate projects from initial plans to delivery, including quotation provision, communicating during the assay process as needed, and seeing the workflow through to data delivery and analysis advice, plus reporting.  The successful candidate will also supervise and mentor support staff and ensure compliance with local standard operating procedures, and all Health and Safety policies. 

The European Institute for Molecular Imaging (EIMI) is an interdisciplinary institute within the University of Münster developing imaging methods allowing to visualize molecular processes inside organisms, tissues and cells. With the help of imaging, we perform cutting-edge research in vascular, inflammatory, infectious, neurodegenerative diseases, and cancer. The EIMI is located in the Multiscale Imaging Center (MIC), which hosts research groups from our University combining a broad range of state of the art imaging technologies for the investigation of biomedical questions.   We are interested in how receptors sense the environment and respond generating selective responses. We will focus on an undervalued receptor family, plexins. These receptors are involved in neuronal development, but also in shaping the cardiovascular, musculoskeletal systems and kidney. Further, plexins regulate immune responses and cancer becoming an attractive drug target.   The 2-year position is funded by an Emmy Noether DFG grant and aims to combine single-molecule localization methods and cell biology to decipher the stoichiometry and dynamics of plexin receptors in living cells, the role of ligand binding and ligand-independent mechanosensing.   What we expect:

• The candidate should hold a PhD in Life Sciences (finished no longer than 3 years ago)
• Strong interest in single molecule localization microscopy methods
• Experience with lab work (confocal microscopy and SMLM)
• We encourage applicants with a broad experimental-analytical interest, as the job holder will contribute both to the development of new methods and their application to investigate the organization and dynamics of plexin receptors in the context of cancer
• Oral and written communication skills - English (required) and German (desired)
• Ability to work effectively in an interdisciplinary team We seek a highly motivated, ambitious, and talented young scientist to join an enthusiastic and collaborative team in an outstanding scientific environment. Proven experience in data acquisition and analysis of advance microscopy imaging techniques (e.g. confocal microscopy, TIRF, FRET, STORM, DNA-PAINT) is required.   What we offer: 
• Career development in a multidisciplinary and committed research team. Mentorship, creative thinking, problem solving, and teamwork will be strongly promoted
• Work-life balance. Münster is one of the cities with best quality of life!
• Modern infrastructure, international and collaborative research environment

We are looking forward to your online application by 15.01.2025 including as a single PDF (Cover letter describing your research interest and why you are suitable for the position (maximum 1 page); CV including a list of relevant publications; Copy of the official academic transcript of your degree; Names, e-mail addresses, and telephone numbers of 2 academic references).

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved by size and medical successes alone. The individual commitment counts above all. We need your commitment so that even with little things we can achieve great things for our patients. There are many possibilities open for you so that you may develop with them.

Team context The revolution in imaging technologies has led to the need to share, integrate and reuse image data in a comprehensive way. EMBL-EBI is a world-leader in the archival and dissemination of biological image data, operating the BioImage Archive and EMPIAR (the Electron Microscopy Public Image Archive), which together provide the means to store and search life science datasets from all imaging technologies at all scales and across all modalities. Role overview and purpose This role will provide a key link between the UK biological imaging community and EMBL-EBI’s imaging data resources. The post-holder will work closely with facility staff, experimental biologists and image analysts to understand and support their needs in image data management, annotation and publication. They will build on this knowledge to design and deliver training materials for skills training in image data stewardship within the UK, and hence build a strong community of practice.

Advanced Light Microscopy & Image Analysis (ALM) Technology Platform is looking for a curious, creative, and motivated Imaging Scientist/Postdoc with a background in fluorescence microscopy and/or light-sheet imaging and molecular/cellular biology (part-time, 30 hrs/week) to implement correlative light-sheet and MR imaging of cardiovascular structures in the frame of a VASBIO grant funded project and to support the ALM team in everyday user support. ALM as part of the MDC scientific infrastructures supports 17 imaging setups and enables a wide portfolio of imaging technologies, ranging from super-resolution, TIRF and confocal microscopy to light-sheet imaging (Blaze UM, Zeiss Z7) and 2-Photon/intravital microscopy as well as high-multiplex spatial phenotyping. In addition, ALM supports researchers with sample clearing & labelling and image data analysis. In collaboration with MDC researchers, ALM works to advance imaging methodologies and deepen insights into disease mechanisms. https://www.mdc-berlin.de/advanced-light-microscopy Job Description The tasks of the imaging specialist include (but are not limited) to two main duties: In the frame of a VASBIO grant-funded project in collaboration between ALM and the Berlin Ultrahigh Field MRI facility at MDC: ·       Establishment and optimization of sample clearing and labeling as well as light-sheet imaging of cardiovascular tissue structures. ·       Optimization of data processing and analysis of light-sheet images and correlation with MRI images. As part of the general ALM user and project support: ·       Support researchers by training, assistance and troubleshooting in executing advanced imaging experiments, with a focus on confocal microscopy. ·       Maintain microscopes in optimal working condition. This position is limited to 1 year. For inquiries, please contact: Dr. Anje Sporbert (ALM TP leader): asporb@mdc-berlin.de and Dr. Min-Chi Ku (Berlin Ultrahigh Field MRI facility): min-chi.ku@mdc-berlin.de

Requirements Applicants should have a degree (MSc required, PhD preferred) in life sciences, physics or similar. Profound experience in the area of light microcopy (fluorescence microscopy and additional advanced microscopy methods) is preferred for this position. Expertise in light-sheet imaging, sample clearing or data processing would be a strong plus.   Further requirements are:

• passion scientific technology support and service attitude, self-motivation, pro-active attitude, responsible and independent project handling
• motivation and interpersonal skills to interact with researchers
• excellent organizational and communication skills
• professional command of both spoken and written German or English

The Vienna BioCenter Core Facilities (VBCF) provide cutting-edge research infrastructure and expertise that form the foundation of groundbreaking discoveries at the Vienna BioCenter (VBC), home to multiple research institutes (including IMP, IMBA, GMI, Max Perutz Labs, University of Vienna Biology Building), companies, and around 2,000 scientists. Situated at the VBC campus, the VBCF GmbH provides scientific services to research on campus and beyond, supported by the extensive expertise of over 80 trained scientists and technicians. The VBCF is currently seeking a:

Head of Plant Sciences Core Facility (f/m/d, full-time) for our Plant Sciences team. This role involves advancing our cutting-edge research in high-throughput plant phenotyping, while also overseeing the maintenance and optimization of phytotrons to support essential plant growth and experimental services. A detailed overview of our offered services can be found on our website.

• Key responsibilitiesLead and manage a state-of-the-art, multi-sensor, high-throughput plant phenotyping research infrastructure - #PHENOPlant.
• Lead and further develop a diverse service portfolio: high-throughput plant phenotyping - technology development (prototyping) - software development - data analysis.
• Lead and evaluate scientific projects to drive innovations in plant phenotyping, focusing on high-throughput data acquisition and image processing.
• Coordinate and further develop the Austrian Plant Phenoytping Network (APPN) supporting the EU ESFRI EMPHASIS project.
• Oversee the routine operation and maintenance of phytotrons and glasshouses, ensuring optimal plant growth conditions for research.
• Manage lab organization and instrument maintenance to ensure efficient workflows and consistent service quality.
• Develop and implement new protocols to enhance the facility’s service offerings in plant sciences.
• Train and guide an interdisciplinary team, fostering a collaborative and customer-oriented environment.
• Engage with national and international customers to understand their scientific needs and provide impactful research support. Carry out business development and new customer acquisition.

Pictura Bio is seeking a skilled Prototype Engineer for a short-term project focused on developing a smartphone-enabled fluorescence microscopy system for imaging pathogens. The project entails building and refining a compact, smartphone-compatible imaging setup. The ideal candidate will have a strong background in optics and fluorescence microscopy, with hands-on experience adapting optical systems for smartphone integration. Requirements:

1. Deep expertise in optics and fluorescence microscopy.
2. Proven experience in designing and prototyping smartphone-compatible imaging systems.
3. Strong ability to work independently and troubleshoot technical challenges.
4. Availability for a short-term, hands-on project. How to Apply: Please contact nicolas.shiaelis@pictura.bio.

Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges. Are you passionate about image analysis, software development, and collaboration with scientists? Do you have a knack for designing and developing efficient image analysis pipelines? We are looking for an experienced Data Scientist / Image Analysis Developer to join our team and contribute to cutting-edge research in the field of genomics. As a key member of our imaging team, you will work closely with scientists and engineers to develop innovative solutions for interdisciplinary scientific problems.

About the Role As Senior Data Scientist, you will be responsible for:

• Designing and developing image analysis pipelines for spatial genomics and high-content screening data
• Collaborating with our team of scientists and engineers to understand imaging data and develop efficient solutions
• Troubleshooting problems on a day-to-day basis and escalating issues outside of your expertise
• Communicating results through presentations, posters, and meetings with collaborators
• Executing and maintaining existing imaging-based analysis pipeline services

About You To excel in this role you will need the following:

• MSc or Ph.D. in a relevant quantitative discipline (e.g., Computer Science, Computational Biology, Genetics, Bioinformatics)
• Experience working with image analysis tools such as QuPath, OMERO, Napari, and Fiji
• Knowledge of software development good practices and collaboration tools (git-based version control, Python package management, Docker/Singularity)
• Excellent communication skills to explain complex image analysis algorithms to non-technical stakeholders
• Ability to organize, plan, and prioritize tasks or projects

The Bio-Imaging Resource Center (BIRC) at the Rockefeller University in New York City is seeking a motivated full-time microscopist to advise and train users on our commercial microscopes and to push these systems to new levels! In addition, the applicant will liaise with the image analysts in the BIRC and also with our optical engineer, who is building pre-commercial light sheet systems in our satellite laboratory.

Summary: The Ragon Institute is a highly unique, innovative, and collaborative research center at the forefront of biomedical science. Founded by Massachusetts General Hospital, MIT, and Harvard, the Ragon vision is a bold one: to harness the power of the immune system to prevent and cure human disease on a global scale. This vision is pursued and advanced every day by a group of highly motivated individuals. The Ragon Institute, at every level, depends upon collaboration, compassion, dedication, and innovation.  It is a results-oriented organization that seeks people who not only embrace these values but who thrive in teams and want to work in a dynamic environment.

At the Ragon Institute, people are our greatest asset.  In this role, the Microscopy Director will be an integral part of the evolution of the organization.  They will be responsible for overseeing the daily operations and financial solvency of the Ragon’s current microscopy core, but they will also play a critical role in helping to evolve and grow the facility.  Specifically, the Microscopy Director will manage state-of-the-art fluorescence microscopy equipment s, supporting a wide range of scientific research across multiple disciplines, including immunology, tissue biology, cell biology, and microbiology. The Director will also be responsible for ensuring the microscopy facility operates at the highest standards, providing technical expertise, training, and support to researchers, and driving innovation in imaging techniques and technologies.

The ideal candidate is a highly skilled scientist with deep expertise in advanced microscopy techniques, a proven track record of supporting cutting-edge research, enjoy collaborating with multi-disciplinary teams, thrive on creating new processes, and possess strong leadership and management abilities.  Ultimately, they will be a strategic thought partner and a trusted advisor to the core users and Ragon leadership team. Primary Duties and Responsibilities: Leadership and Oversight:

• In collaboration with end-users, develop and implement a strategic plan for the facility, ensuring that it stays at the forefront of microscopy technology and research capabilities.
• Compare the core to peer institutions’ resources through benchmarking studies.
• Identify appropriate facility operating metrics and regularly analyze data.
• Develop a process to track core utilization and optimization.
• Present programmatic and financial data analysis on core performance to a variety of audiences.
• Advise the Executive Team and Faculty regarding the scientific appropriateness and value of current / new equipment for the core.
• Ensure compliance with MGH, Ragon, and US Federal regulations as they apply to core facilities. Facility Management and Operations:
• Lead and manage all microscopy operations, ensuring the smooth functioning and availability of instruments, technology platforms, and services to researchers.
• Determines and writes user policies for the facility.
• Stay updated on the latest microscopy advancements and disseminate best practices across the research community.
• Develop educational programs, workshops, and seminars to enhance the knowledge and skills of microscopy users within the organization.
• Lead the training and mentorship of scientists, students, and staff in microscopy techniques, image acquisition, and analysis. Research Support and Collaboration:
• Work closely with researchers across various scientific disciplines to design and optimize microscopy experiments, providing guidance on the best imaging techniques, protocols, and analyses for their scientific questions.
• Collaborate with investigators to develop novel imaging approaches and methods, facilitating high-impact publications and discoveries.
• Act as a liaison between the microscopy core and research groups, ensuring that services are aligned with the evolving needs of the scientific community. Financial Oversight
• Collaborate with the Ragon Finance Team and Imaging Committee in creating long and short-term business plans and yearly budgets.
• Monitor budgets to ensure fiscal solvency.
• Report on core performance; investigate and provide resolution options to remedy variances from expected to actual business and performance indicators.
• Maintain accurate records of facility usage for reporting and billing purposes.
• Oversee safety protocols and ensure compliance with all relevant regulations regarding the use of microscopes and related technologies. Equipment Management and Innovation:
• Oversee the maintenance, calibration, and upgrades of all microscopy equipment, ensuring optimal performance and data quality.
• Drive innovation by introducing new microscopy technologies, imaging modalities, and advanced techniques such as high-resolution multiplexed confocal imaging (both in tissues and cells), cleared 3D organ imaging, multiphoton imaging, spatial omics, FLIM, and live-cell imaging.
• Collaborate with vendors and suppliers to evaluate and acquire new instruments that enhance the facility’s capabilities.
• Advise the space committee around the physical space requirements for institutional shared research cores. Data Management and Analysis:
• Oversee data acquisition, processing, and image analysis workflows, ensuring that high-quality imaging data is collected and stored appropriately.
• Implement and provide support for advanced image analysis software and tools (e.g., Imaris, Avia, Arivis, Napari, ImageJ etc.), ensuring that researchers can effectively analyze complex datasets.
• Promote the integration of microscopy data with other scientific datasets to support multi-modal analysis and advanced research. Grant Writing and Funding:
• Support researchers in the preparation of grant applications by providing technical expertise related to microscopy techniques and experimental design.
• Lead and contribute to the development of facility-based grants to enhance the microscopy core’s capabilities and support infrastructure improvements.     Education:
• PhD in biology, biophysics, biomedical engineering, or a related field with significant experience in advanced microscopy techniques.

Experience:

• 7+ years of experience in fluorescence microscopy, including but not limited to confocal, live-cell  light sheet, multiphoton, and super-resolution microscopy, with a strong record of publications or research contributions. Experience with modern multiplexed tissue/organ imaging techniques is highly advantageous.
• Ideally, extensive experience in managing or directing a microscopy core facility or research laboratory.
• Proven ability to collaborate with and support researchers in designing microscopy experiments across diverse scientific disciplines.
• Prior experience in an academic setting highly preferred.

Skills:

• Deep expertise in advanced microscopy techniques and imaging modalities.
• Proficient in microscopy software and image analysis tools (e.g., ImageJ, Imaris, or similar).
• Strong leadership and management skills, with experience in supervising staff and training users.
• Excellent communication and interpersonal skills to interact with a broad range of researchers and stakeholders.
• Ability to troubleshoot complex technical issues and optimize imaging protocols for scientific rigor.

Preferred Qualifications:

• Significant experience with light and fluorescence microscopy, including live-cell confocal, super-resolution, light sheet and other  and specialized imaging techniques.
• Experience in quantitative image analysis. A familiarity with modern machine learning and artificial intelligence applications in image analysis is a benefit.
• Experience with grant writing and securing funding for microscopy-related research or infrastructure.

Work Setting: M-F, 8:30 am – 5 pm, on-site

The above job description details the major duties and qualifications of the listed position. The individual hired to this position confirms that they are able to perform all duties outlined. Although the specific duties and responsibilities of this position may vary slightly, the supervisor of this position will ensure that the individual hired to this position is trained and qualified to complete each task assigned.    EEO Statement   Massachusetts General Hospital is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.    Primary Location MA-Cambridge-MGH Ragon Institute Work Locations MGH Ragon Institute 600 Main St  Cambridge 02139 Job Research - Other Organization Massachusetts General Hospital(MGH) Schedule Full-time Standard Hours 40 Shift Day Job Employee Status Regular Recruiting Department Ragon Institute Job Posting Oct 11, 2024

Norlin lab is expanding and seeking new team members. We are looking for a postdoctoral fellow in optics engineering and microscopy driving and or supporting projects in light-sheet/oblique plane microscopy, lensless-, smart- and light-field microscopy. In these highly collaborative projects, you will have the chance to develop novel microscopy techniques to cover new grounds in single cell and tissue biology. The lab is located at the department of experimental medical science and has extensive collaborations with researchers at the medical faculty as well as Nanolund and the Lund university bioimaging centre.   We’re seeking candidates with a Ph.D. in optics engineering, light microscopy, or related fields with practical experience in building optical setups. Knowledge of molecular biology / life science is recommended but no requirement. We are looking for an openminded, positive and self-motivated team player with excellent written and verbal communication skills in English. 

Empire Innovations Program/Cluster Hire with the focus on Biological Imaging, Biosensors, Cell Dynamics Analysis, and Optogenetics Department of Cell & Developmental Biology and Department of Biochemistry & Molecular Biology, SUNY Upstate Medical University, Syracuse, New York.    The Departments of Cell & Developmental Biology and Biochemistry & Molecular Biology at SUNY Upstate Medical University in Syracuse, New York, are seeking cluster hires for two tenure-track faculty positions. The cluster hire program is aimed at attracting faculty who are developing new technologies in the areas of imaging, image analysis, cell dynamics analysis, biosensors for detecting disease biomarkers and point-of-care diagnostics, and photomanipulation/optogenetic approaches with potential applications to human health and disease. These Empire Innovation Scholars will complement additional junior faculty hires in the two departments as part of a coordinated expansion effort.

Candidates must have a PhD or equivalent degree in cell or molecular biology, biomedical engineering, biochemistry, physics, or a related field, and currently hold the rank of an assistant or associate professor or a comparable leadership position in private industry. Applicants should have established track records of funding and research productivity. Successful candidates are expected to develop and maintain a vigorous extramurally funded research program and participate in the education of medical and graduate students.   The successful candidates will join a thriving community of over 20 investigators with strengths in using intravital imaging and live-cell imaging to study cardiovascular development, pathogenesis of cancer and neurodegenerative diseases, development and regeneration of vision photoreceptors and immune disorders and development of biosensors and diagnostic assays. Academic appointment will be commensurate with experience and will carry the title of an Associate Professor of Empire Innovation or Professor of Empire Innovation. Preference will be given to candidates currently at the Assistant or Associate Professor level, or comparable rank in industry. 

This position is fully state-supported with a 12-month base salary, excellent health and retirement benefits, and competitive start-up funds. Our faculty are well supported by state-of-the-art imaging resources and outstanding institutional core facilities.      Located in central NY, Syracuse provides a diverse, dynamic, and affordable metropolitan environment with easy access to outstanding recreational opportunities of the Adirondack Mountains and the Finger Lakes. Proximity of SUNY Upstate to Syracuse University and SUNY ESF campuses fosters productive scientific interactions and unique collaborative funding opportunities.    Please apply online to job #82494 at https://bit.ly/UpstateEIP and upload a cover letter, a curriculum vitae, and a research statement (up to three pages) consisting of a summary of accomplishments and description of future plans. Letters of recommendation will be requested separately. 

Review of applications will start November 15, 2024 and continue until the positions are filled.

Further information about the Cell & Developmental Biology and Biochemistry & Molecular biology departments, including additional open positions, can be found at https://www.upstate.edu/cdb/ and https://www.upstate.edu/biochem/. Applicants will be considered for primary appointment in either department depending on fit, but applicants are encouraged to indicate their preference in the cover letter.

At SUNY Upstate Medical University we strive to promote a professional environment that encourages varied perspectives from faculty members with diverse life experiences. A respect for diversity is one of our core values. We are committed to recruiting and supporting a rich community of outstanding faculty, staff and students. We actively seek applications from women and members of underrepresented groups to contribute to the diversity of our university community in support of our teaching, research and clinical missions.

Job Description Summary Supports microscopy related research and teaching in the Microscopic Imaging Core of Wake Forest University Biology by assisting the Director of Microscopy.

Job Description Essential Functions:

• Trains new users and assists in utilization of microscopes and related equipment.
• Maintains microscopes and related equipment in a clean and highly operational state.
• Communicates an excitement about imaging-related science to new students and visitors.
• Facilitates scheduling of equipment use and related record keeping/reporting.
• Reports to and coordinates overall activities with the microscopy director.
• Assists the director in other microscopy facility related directives as assigned.
• Assists undergraduates, graduate students, and faculty with design and implementation of experimental protocols related to microscopy by understanding research goals and needs of individual facility users.

Additional Job Description Accountabilities:

• Responsible for own work.
• Provides training and assists in the supervision of graduate and undergraduate student researchers.
• Reports activities and problems to the facility director. Physical Requirements:
• Sedentary work primarily involving sitting/standing; communicating with others to exchange information; repeating motions that may include the wrists, hands, and/or fingers; and assessing the accuracy, neatness, and thoroughness of the work assigned. 
• Ability to travel 7 miles between Innovation Quarter and main Reynolda campus (university shuttle or personal car) Disclaimer: This position profile identifies the key responsibilities and expectations for performance. It cannot encompass all specific job tasks that an employee may be required to perform. Employees are required to follow any other job-related instructions and perform job-related duties as may be reasonably assigned by the employee’s supervisor.

We have funded postdoc positions available in the Carpenter-Singh lab in Cambridge MA USA (Broad Institute of Harvard and MIT), paying $70,000 (or more with years of experience post-PhD) with a flexible start date.

There are two projects: - Rapidly identifying disease phenotypes from rare disease variants, and drugs to reverse their impact (as part of the NIH IGVF Consortium https://www.youtube.com/watch?v=8RcsC4a2Ews&list=PLJG0u60zazOtRAwamVGhaJ6eGqh-HASvw&index=6) - Using Cell Painting, transcriptomics, and proteomics data to predict toxicity of drugs and agrochemicals (as part of the OASIS Consortium https://oasisconsortium.org)

Both projects will have copious data produced by this time next year!

Summary Elephas, a Madison, WI-based biotechnology start-up company, seeks a talented individual to join our team as a Software Engineer specializing in fluorescence microscopy, multi-photon or Optical Coherence Microscopy (OCM) microscopes for biological applications. Applicants should be comfortable in a fast-paced and collaborative environment. The successful candidate will be a skilled and experienced software engineer who will contribute to developing, optimizing, and validating Elephas’ cancer diagnostics platform.

Essential Duties and Responsibilities

• Develop and optimize image analysis, signal processing and visualization solutions for combining multi-photon, OCT/OCM, slide scanning, and widefield microscopes used in biological imaging.
• Collaborate with interdisciplinary teams to understand and translate system requirements into efficient and reliable software solutions.
• Analyze and troubleshoot system issues, provide technical support, and propose innovative solutions.
• May assist with control system development (novel development).
• Stay up-to-date with the latest advancements in imaging technologies, identifying opportunities for improvement and innovation.
• Follow a regulated software development methodology in an agile environment.
• Align with the Elephas values: Deliver patient-centric solutions, Deliver quality, Be science-driven, Be curious and innovative, Be generous and honest, and Be a good partner and teammate.

Education/Experience/Skills

• Master’s or PhD in Computer Science, Computer Engineering, Applied Mathematics or a similar field, or applicable industry experience.
• Strong experience with C++ and C, with a minimum of 5 years of experience.
• Proficiency in troubleshooting compile-time errors.
• Expertise in multiprocess communications.
• Experience in combining languages, such as using a C++ library in Python or Matlab.
• Proficiency in C# preferred.
• Strong graphics programming skills in DirectX, Vulcan, OpenGL, Metal, or similar.
• Experience with time-lapse animation or gaming interface and design is preferred.
• Proficiency in image analysis.
• Experience in high-performance computing.
• Experience coding in a team environment, including version control and code reviews.
• Proficiency with Linux, Windows, and Mac operating systems.
• Experience with Matlab, Octave, and R is preferred.
• Strong mathematical skills
• Strong problem-solving and analytical skills, with the ability to work independently and collaboratively in a dynamic team environment.
• Excellent communication skills and the ability to effectively present technical concepts to technical and non-technical stakeholders.   We offer our employees competitive compensation and benefits, including paid time off, health insurance, life insurance, flexible spending accounts, a 401(k) plan, and stock options. Relocation assistance is available. Qualified candidates should forward their resumes to mcostin@elephas.com or apply through the careers section on our website, https://elephas.com/join-elephas.

DISCLAIMER The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.   We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

The FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine is seeking a talented, skilled, and highly motivated researcher to assume the role of Senior Staff Scientist (90282BR). The candidate will play a leadership role in managing and performing electron microscopy (EM) sample preparation and FIB-SEM sample preparation operations. At the forefront of volume Electron Microscopy, the F-SCC utilizes the state of the art enhanced Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for large volume imaging with nanometer isotropic resolution. Under supervision of the Director, the candidate will be responsible for optimizing the existing electron microscopy (EM) sample preparation protocols of biological specimens, developing new methods for clinical specimens, and establishing an automated EM sample preparation pipeline. The candidate is expected to perform independent research, experiments, and laboratory techniques, and work closely with supervisor, group members, and collaborators.